Matthew W. State, MD, PhD

Professor (Adjunct) in the Child Study Center; Co-Director, Yale Program on Neurogenetics

Research Interests

Autistic Disorder; Mental Disorders; Child Development Disorders, Pervasive; Tourette Syndrome; Schizophrenia, Childhood; Tic Disorders; Asperger Syndrome

Research Organizations

Kavli Institute for Neuroscience

Program in Neurodevelopment and Regeneration

Research Summary

Our lab is interested in identifying and characterizing genes and genetic mechanisms involved in neuropsychiatric and neurodevelopmental disorders of childhood. Currently we are focused on Tourette syndrome (TS) and Obsessive Compulsive disorder (OCD), Autism and related pervasive developmental disorders, childhood onset schizophrenia and structural brain disorders. We have a long standing interest in the contribution of rare variation to these syndromes and focus on gene discovery as an avenue to elaborate molecular mechanisms of disease. We currently employ a range of approaches including traditional gene mapping in families demonstrating Mendelian inheritance, molecular cytogenetic analyses of de novo chromosomal rearrangements, and high throughput genomic approaches including genome wide copy number analyses and massively parallel sequencing.

Selected Publications

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Contact Info

Matthew W. State, MD, PhD
Lab Location
State LabThe Anlyan Center
300 Cedar Street, Ste S-330/3rd

New Haven, CT 06519
Office Location
The Anlyan Center
300 Cedar Street, Ste Suite 341A

New Haven, CT 06519
Mailing Address
Yale Child Study CenterPO Box 207900
230 South Frontage Road

New Haven, CT 06520-7900